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Johnson & Johnson announces new TREMFYA® (guselkumab) data showing durable 3-year outcomes in moderate to severe Crohn’s disease and expanding evidence in perianal fistula

Johnson & Johnson (JNJ)Johnson & JohnsonClinical readout

BEERSE, BELGIUM ( 19 October 2026 ) – Johnson & Johnson today announced new data that further expands the clinical evidence supporting TREMFYA ® (guselkumab) in Crohn's disease (CD) at the 2026 United European Gastroenterology Week (UEG Week). Research from the Phase 3 GALAXI studies shows durable efficacy and a consistent safety profile for guselkumab through three years (Week 144) of maintenance treatment in adults with moderately to severely active CD, reinforcing its long-term benefit in this chronic, progressive disease. 1 Additionally, late-breaking one-year results from the Phase 3 FUZION study showed that guselkumab maintained or improved fistula remission through Week 48 in adults with CD with perianal fistula. 2

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Johnson & Johnson

Johnson & Johnson is a global healthcare leader spanning innovative medicines and medtech. Its scale, diversification, and broad therapeutic reach make it one of the most important names in the sector.

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