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Spyre Therapeutics Reports Third Quarter 2026 Financial Results and Provides Corporate Update

Spyre Therapeutics, Inc. (SYRE)Spyre Therapeutics, Inc.Earnings

Announced positive topline induction data for SPY003 from Part A of the Phase 2 SKYLINE trial (“SKYLINE”), completing proof-of-concept for all three monotherapies in inflammatory bowel disease (“IBD”). SKYLINE Part B is enrolling ahead of schedule, enabling the Company to increase enrollment and provide topline induction results for three potential best-in-indication combinations, which are expected in Q3 2027

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Spyre Therapeutics, Inc.

Long-Acting Immunology Antibodies Spyre Therapeutics develops extended-half-life antibodies and antibody combinations for inflammatory bowel disease and rheumatic diseases. Its strategy is to combine established immunology targets with less frequent subcutaneous dosing and, ultimately, multi-mechanism regimens. SKYLINE IBD Platform The...

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