C4 Therapeutics to Participate in the 8th Annual Evercore Healthcare Conference

C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science, today announced that C4T management will participate in a fireside chat at the 8 th Annual Evercore Healthcare Conference taking place from December 2 - 4, 2025 in Coral Gables, Florida.

Fireside Chat Details: Event: 8 th Annual Evercore Healthcare Conference Date/Time: Wednesday, December 3 rd , 2025 at 3:25 pm ET

A live webcast will be available on the Investors section of the company’s website at www.c4therapeutics.com . An archived replay of the webcast will be available for approximately 90 days following the live event.

About C4 Therapeutics

C4 Therapeutics (C4T) (Nasdaq: CCCC) is a clinical-stage biopharmaceutical company dedicated to delivering on the promise of targeted protein degradation science to create a new generation of medicines that transforms patients’ lives. C4T is progressing targeted oncology programs through clinical studies and leveraging its TORPEDO ® platform to efficiently design and optimize small-molecule medicines to address difficult-to-treat diseases. C4T’s degrader medicines are designed to harness the body’s natural protein recycling system to rapidly degrade disease-causing proteins, offering the potential to overcome drug resistance, drug undruggable targets and improve patient outcomes. For more information, please visit www.c4therapeutics.com.

Contacts:

Investors: Courtney Solberg Associate Director, Investor Relations [email protected]

Media: Loraine Spreen Senior Director, Corporate Communications & Patient Advocacy [email protected]