Annovis Announces Two Presentations at the AD/PD™ 2026 International Conference

Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced two presentations at the 20th International Conference on Alzheimer’s and Parkinson’s Diseases ( AD/PD™ 2026 ), taking place March 17-21, 2026, in Copenhagen, Denmark.

The presentations will highlight clinical data supporting buntanetap's treatment effect in PD with a particular focus on cognition and biomarker findings, and provide an update on the ongoing pivotal Phase 3 trial in early AD.

Details

Presentation #1 (ID:3581)

Title: Buntanetap Treatment in Parkinson’s Disease Patients with MCI or Mild Dementia

Presenter: Cheng Fang, Ph.D., Senior VP, Research & Development

Theme C: α-Synucleinopathies

Presentation #2 (ID:3582)

Title: A Dual 6-month & 18-month Randomized, Placebo-Controlled, Double-Blind Clinical Trial Investigating Efficacy and Safety of Buntanetap in Early Alzheimer’s Participants

Presenter: Cheng Fang, Ph.D., Senior VP, Research & Development

Theme A: β-Amyloid Diseases

“We are proud to present the continued progress in enrollment for our Alzheimer’s disease pivotal study, reflecting strong engagement from both investigators and patients,” commented Cheng Fang, Ph.D., Senior VP, Research & Development at Annovis. “Additionally, we will present the biomarker data from our Parkinson’s disease study that further support buntanetap’s therapeutic efficacy and mechanism of action.”

AD/PD™ 2026 is a leading international conference dedicated to neurodegenerative diseases, convening top medical and scientific experts to present novel findings that advance understanding of disease mechanisms and improve treatment strategies for conditions such as Alzheimer’s and Parkinson’s.

Additional information and presentation updates are available on the conference’s official website .

About Annovis Headquartered in Malvern, Pennsylvania, Annovis Bio, Inc. (NYSE: ANVS) is a Phase 3 clinical-stage biotechnology company developing treatments for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The Company's lead drug candidate, buntanetap (formerly posiphen), is an investigational once-daily oral therapy that inhibits the translation of multiple neurotoxic proteins, including APP and amyloid beta, tau, alpha-synuclein, and TDP-43, through a specific RNA-targeting mechanism of action. By addressing the underlying causes of neurodegeneration, Annovis aims to halt disease progression and improve cognitive and motor functions in patients. For more information, visit www.annovisbio.com and follow us on LinkedIn , YouTube , and X .

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Forward-Looking Statements This press release contains forward-looking statements under the Securities Act of 1933 and the Securities Exchange Act of 1934, as amended. Actual results may differ due to various risks and uncertainties, including those outlined in the Company’s SEC filings under “Risk Factors” in its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no obligation to update forward-looking statements except as required by law.

Contact Information: Annovis Bio Inc. 101 Lindenwood Drive Suite 225 Malvern, PA 19355 www.annovisbio.com

Investor Contact: Alexander Morin, Ph.D. Director, Strategic Communications Annovis Bio [email protected]