企業プロフィール
Replimune Group 株価・ニュース・カタリスト
- ティッカー:
- REPL
- 取引所:
- NASDAQ
- セクター:
- Biopharma
- 所在地:
- United States
株価パフォーマンス
14.63 USD (-2.27%)
終値
最終更新: 2026年8月17日
732M USD
時価総額
株価変動の要因
The latest company update was “Replimune Reports Fiscal First Quarter 2027 Financial Results and Provides Corporate Update”. REPL changed 1.45% and closed at $14.97 on Aug 14, 2026, indicating a relatively limited closing-price reaction to this earnings update.
企業概要
Oncolytic Immunotherapy Platform
Replimune develops engineered herpes-simplex-virus-based immunotherapies that selectively replicate within tumors, directly destroy cancer cells, release tumor antigens, and stimulate systemic antitumor immunity. Its viruses are armed with immune-activating components intended to enhance local tumor killing and complement checkpoint inhibitors.
TUDRIQEV
TUDRIQEV, previously known as RP1, is an FDA-approved oncolytic therapy encoding a fusogenic GALV-GP-R protein and GM-CSF. It is approved under the accelerated approval pathway in combination with nivolumab for adults with unresectable advanced cutaneous melanoma whose disease progressed on a PD-1 antibody-based regimen.
IGNYTE-3 Confirmatory Program
The global Phase 3 IGNYTE-3 study is evaluating TUDRIQEV plus nivolumab against physician's-choice therapy in advanced melanoma after anti-PD-1 treatment. The study is intended to verify clinical benefit and support continued approval, with overall survival as the primary endpoint.
RP2
RP2 builds on the same oncolytic HSV-1 backbone as TUDRIQEV and additionally expresses an anti-CTLA-4 antibody-like molecule. The design seeks to concentrate CTLA-4 blockade within tumors and tumor-draining lymph nodes while limiting systemic exposure.
Metastatic Uveal Melanoma
The registration-directed REVEAL study evaluates RP2 plus nivolumab against ipilimumab plus nivolumab in metastatic uveal melanoma. The Phase 2/3 trial uses overall survival and progression-free survival as primary endpoints.
今後のカタリスト
- US commercial launch of TUDRIQEV within 60 days of its August 6, 2026 FDA approval.
- Transition of the RP2 REVEAL study into Phase 3 in the first quarter of 2027.
- Primary overall-survival readout from the Phase 3 IGNYTE-3 confirmatory study in 2030.
最近のニュース
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類似銘柄
事業成熟度、治療領域、カタリスト傾向が近い同業銘柄です。