Company Profile

Amylyx Stock Price, News & Catalysts

Ticker:
AMLX
Exchange:
NASDAQ
Sector:
Biopharma
Location:
United States

Stock performance

28.08 USD (-3.51%)

Close

Last updated: October 1, 2026

1.48B USD

Market cap

Why the stock is moving

As of Oct 1, 2026, AMLX closed down 3.51% at $28.08. No new same-company headline was identified in the current news window.

Company overview

Neuroendocrine and Rare-Disease Biotechnology Company

Amylyx Pharmaceuticals develops therapies for endocrine and neurological diseases with limited treatment options. Its portfolio combines peptide therapeutics, antisense oligonucleotides, and small-molecule approaches across post-bariatric hypoglycemia, amyotrophic lateral sclerosis, Wolfram syndrome, and related disorders.

Avexitide and Post-Bariatric Hypoglycemia

Avexitide is a GLP-1 receptor antagonist designed to reduce the excessive insulin response that drives post-bariatric hypoglycemia. It is the company's lead late-stage asset and has received Breakthrough Therapy designation for both post-bariatric hypoglycemia and congenital hyperinsulinism.

Neurology Programs

AMX0114 is an antisense oligonucleotide targeting calpain-2 for amyotrophic lateral sclerosis. The program is in first-in-human development and reflects Amylyx's effort to build a mechanistically differentiated neurology pipeline beyond its earlier commercial history.

Wolfram Syndrome Development

AMX0035 is being studied in Wolfram syndrome, a rare genetic disorder affecting pancreatic beta cells, vision, and neurological function. Open-label clinical findings have supported continued discussions with the FDA regarding a potential Phase 3 study.

Next-Generation Endocrine Pipeline

AMX0318 is a long-acting GLP-1 receptor antagonist being developed for post-bariatric hypoglycemia and other rare endocrine diseases. Amylyx is using external research collaborations to identify additional peptide candidates and broaden its endocrine portfolio.

Future catalysts

  • Topline Phase 3 LUCIDITY data for avexitide in post-bariatric hypoglycemia in late August or early September 2026.
  • Potential avexitide NDA submission and commercial launch in 2027, subject to positive data and regulatory review.
  • IND filing for long-acting GLP-1 receptor antagonist AMX0318 in 2027.

Recent news

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    Frequently Asked Questions

    What is the current stock price of Amylyx (AMLX)?

    Amylyx (AMLX) most recently closed at 28.08 USD, a -3.51% move versus the previous session.

    What is the market cap of Amylyx (AMLX)?

    Amylyx currently has a market capitalization of 1.48B USD on BioPharmSignal.

    What does Amylyx do?

    Neuroendocrine and Rare-Disease Biotechnology Company Amylyx Pharmaceuticals develops therapies for endocrine and neurological diseases with limited treatment options. Its portfolio combines peptide therapeutics, antisense oligonucleotides, and small-molecule approaches across post-bariatric hypoglycemia, amyotrophic lateral sclerosis, Wolfram syndrome, and...

    On which exchange is AMLX stock listed?

    Amylyx (AMLX) is associated with NASDAQ, United States, Biopharma.

    What is GLP-1?

    IND filing for long-acting GLP-1 receptor antagonist AMX0318 in 2027.

    Which conditions is Amylyx targeting with GLP-1?

    Amylyx is associated with neurology, genetic disease based on its company overview and current catalyst commentary.

    How does Amylyx describe recent progress with GLP-1?

    IND filing for long-acting GLP-1 receptor antagonist AMX0318 in 2027.

    What is Neuroendocrine?

    Neuroendocrine and Rare-Disease Biotechnology Company Amylyx Pharmaceuticals develops therapies for endocrine and neurological diseases with limited treatment options.