# Structure Therapeutics Reports Positive Topline Data from ACCESS Program for its Once-Daily Oral Small Molecule GLP-1 Receptor Agonist, Aleniglipron
Canonical URL: https://biopharmsignal.com/news/GPCR/structure-therapeutics-reports-positive-topline-data-from-access-program-for-its-once-daily-oral-small-molecule-glp-1-receptor-agonist-aleniglipron
Ticker: GPCR
Company: Structure Therapeutics
Source: Structure Therapeutics
Published: 2025-12-08 13:00 EST
Original Source URL: https://ir.structuretx.com
## Summary

Placebo-adjusted mean weight loss of 11.3% (27.3 lbs) with 120 mg dose in the 36-week Phase 2b ACCESS study with a 10.4% adverse event-related treatment discontinuation  Placebo-adjusted mean weight loss up to 15.3% (35.5 lbs) observed with 240 mg dose in the exploratory ACCESS II study at 36 weeks

## Article Body
Placebo-adjusted mean weight loss of 11.3% (27.3 lbs) with 120 mg dose in the 36-week Phase 2b ACCESS study with a 10.4% adverse event-related treatment discontinuation  Placebo-adjusted mean weight loss up to 15.3% (35.5 lbs) observed with 240 mg dose in the exploratory ACCESS II study at 36 weeks
## Recent Company News
- 2026-05-26 20:05 EST — [Structure Therapeutics Announces Participation in Upcoming Investor Conferences](https://biopharmsignal.com/news/GPCR/structure-therapeutics-announces-participation-in-upcoming-investor-conferences) — Source: Structure Therapeutics
- 2026-05-07 20:06 EST — [Structure Therapeutics Reports First Quarter 2026 Financial Results and Recent Highlights](https://biopharmsignal.com/news/GPCR/structure-therapeutics-reports-first-quarter-2026-financial-results-and-recent-highlights) — Source: Structure Therapeutics
- 2026-04-27 20:05 EST — [Structure Therapeutics to Present Aleniglipron, Amylin and Combination Data at the American Diabetes Association 86th Scientific Sessions](https://biopharmsignal.com/news/GPCR/structure-therapeutics-to-present-aleniglipron-amylin-and-combination-data-at-the-american-diabetes-association-86th-scientific-sessions) — Source: Structure Therapeutics
- 2026-04-14 20:05 EST — [Structure Therapeutics Appoints Matthew Lang, J.D. as Chief Operating Officer and General Counsel](https://biopharmsignal.com/news/GPCR/structure-therapeutics-appoints-matthew-lang-j-d-as-chief-operating-officer-and-general-counsel) — Source: Structure Therapeutics
- 2026-03-16 11:00 EST — [Structure Therapeutics Reports Positive Topline Data from Phase 2 ACCESS II Trial with Once-Daily Oral Small Molecule GLP-1 Receptor Agonist, Aleniglipron](https://biopharmsignal.com/news/GPCR/structure-therapeutics-reports-positive-topline-data-from-phase-2-access-ii-trial-with-once-daily-oral-small-molecule-glp-1-receptor-agonist-aleniglipron) — Source: Structure Therapeutics
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