# Erasca Announces Positive Preliminary Phase 1 Dose Escalation Data for Potentially Best-in-Class Pan-RAS Molecular Glue ERAS-0015 in KRAS-Mutant Solid Tumors
Canonical URL: https://biopharmsignal.com/news/ERAS/erasca-announces-positive-preliminary-phase-1-dose-escalation-data-for-potentially-best-in-class-pan-ras-molecular-glue-eras-0015-in-kras-mutant-solid-tumors
Ticker: ERAS
Company: Erasca
Source: Erasca
Published: 2026-04-27 20:01 EST
Original Source URL: https://investors.erasca.com
## Summary

Robust monotherapy efficacy in KRAS G12X NSCLC: 62% uORR in 2L+ and 75% uORR in post-ICI/platinum 2/3L at 16-32 mg QD PAD, and 64% uORR in 2L+ at 24-32 mg QD RDE Robust monotherapy efficacy in 2L KRAS G12X PDAC: 40% uORR at 16-32 mg QD PAD, 42% uORR at 24-32 mg QD RDE, and 50% uORR at 32 mg QD

## Article Body
Robust monotherapy efficacy in KRAS G12X NSCLC: 62% uORR in 2L+ and 75% uORR in post-ICI/platinum 2/3L at 16-32 mg QD PAD, and 64% uORR in 2L+ at 24-32 mg QD RDE Robust monotherapy efficacy in 2L KRAS G12X PDAC: 40% uORR at 16-32 mg QD PAD, 42% uORR at 24-32 mg QD RDE, and 50% uORR at 32 mg QD
## Recent Company News
- 2026-05-27 12:00 EST — [Erasca to Present at the Jefferies Global Healthcare Conference](https://biopharmsignal.com/news/ERAS/erasca-to-present-at-the-jefferies-global-healthcare-conference) — Source: Erasca
- 2026-05-11 20:01 EST — [Erasca Reports First Quarter 2026 Business Updates and Financial Results](https://biopharmsignal.com/news/ERAS/erasca-reports-first-quarter-2026-business-updates-and-financial-results) — Source: Erasca
- 2026-05-11 11:00 EST — [Erasca Announces Clinical Trial Collaboration and Supply Agreement with Merck to Evaluate ERAS-0015 in Combination with KEYTRUDA® (Pembrolizumab)](https://biopharmsignal.com/news/ERAS/erasca-announces-clinical-trial-collaboration-and-supply-agreement-with-merck-to-evaluate-eras-0015-in-combination-with-keytrudar-pembrolizumab) — Source: Erasca
- 2026-05-06 12:00 EST — [Erasca to Present at the Bank of America Securities Health Care Conference](https://biopharmsignal.com/news/ERAS/erasca-to-present-at-the-bank-of-america-securities-health-care-conference) — Source: Erasca
- 2026-04-27 20:01 EST — [Erasca Announces Positive Preliminary Phase 1 Dose Escalation Data for Potentially Best-in-Class Pan-RAS Molecular Glue ERAS-0015 in KRAS-Mutant Solid Tumors](https://biopharmsignal.com/news/ERAS/erasca-announces-positive-preliminary-phase-1-dose-escalation-data-for-potentially-best-in-class-pan-ras-molecular-glue-eras-0015-in-kras-mutant-solid-tumors) — Source: Erasca
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