# Acrivon Therapeutics to Present Pre-Clinical AP3 Data at the 2026 AACR Annual Meeting Revealing Strong Synergy of ACR-368 with ADC Topo 1 Inhibitor Payloads and of both ACR-368 and ACR-2316 with Immune Checkpoint Inhibitors
Canonical URL: https://biopharmsignal.com/news/ACRV/acrivon-therapeutics-to-present-pre-clinical-ap3-data-at-the-2026-aacr-annual-meeting-revealing-strong-synergy-of-acr-368-with-adc-topo-1-inhibitor-payloads-and-of-both-acr-368-and-acr-2316-with-immune-checkpoint-inhibitors
Ticker: ACRV
Company: Acrivon Therapeutics
Source: Acrivon Therapeutics
Published: 2026-03-17 21:54 EST
Original Source URL: https://ir.acrivon.com
## Summary

ACR-368, a CHK1/2 inhibitor in a registrational-intent Phase 2b study, showed potent preclinical synergy with Topoisomerase 1 (Topo 1) inhibitors, commonly used payloads in antibody-drug conjugates (ADCs)  ACR-2316, a WEE1/PKMYT1 inhibitor currently in Phase 1, demonstrated complete and durable

## Article Body
ACR-368, a CHK1/2 inhibitor in a registrational-intent Phase 2b study, showed potent preclinical synergy with Topoisomerase 1 (Topo 1) inhibitors, commonly used payloads in antibody-drug conjugates (ADCs)  ACR-2316, a WEE1/PKMYT1 inhibitor currently in Phase 1, demonstrated complete and durable
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