# NuCana plc (NCNA) Stock Price, News & Catalysts
Canonical URL: https://biopharmsignal.com/company/NCNA
## Company Profile
- Ticker: NCNA
- Exchange: NASDAQ
- Sector: Biopharma
- Location: United Kingdom
- Tags: Oncology
## Stock Data
- Close: 1.4 USD
- Market cap: 8615279.969999999 USD
- Last updated: 2026-09-04
## Business Overview
### ProTide Oncology Company
NuCana applies its ProTide chemistry platform to transform nucleoside analogs into medicines designed to generate higher concentrations of active anticancer metabolites inside tumor cells.
### NUC-7738
NUC-7738 is a ProTide that disrupts RNA polyadenylation and affects multiple components of the tumor microenvironment. It is being evaluated with pembrolizumab in PD-1-inhibitor-resistant melanoma.
### NUC-3373
NUC-3373 is a targeted thymidylate-synthase inhibitor designed to overcome pharmacologic limitations of established fluoropyrimidine therapies.
### Combination Development
NuCana is evaluating tumor types and drug combinations that could support future registrational strategies for both NUC-7738 and NUC-3373.
## Why The Stock Is Moving

As of Sep 4, 2026, NCNA closed down 2.10% at $1.40. No new same-company headline was identified in the current news window.

## Future Catalysts

- Final data from the Phase 2 NuTide:701 expansion study of NUC-7738 in melanoma during 2026.
- FDA guidance on a potential registrational strategy for NUC-7738 in melanoma during 2026.

## Drug Assets

- NUC-7738

## Recent News
- 2026-08-13 20:01 EST — [NuCana Reports Second Quarter 2026 Financial Results and Provides Business Update](https://biopharmsignal.com/news/NCNA/nucana-reports-second-quarter-2026-financial-results-and-provides-business-updat-bbaa9afb) — Source: NuCana plc
- 2026-06-01 12:00 EST — [NuCana Appoints Ian Webster as Chief Financial Officer](https://biopharmsignal.com/news/NCNA/nucana-appoints-ian-webster-as-chief-financial-officer) — Source: NuCana plc
- 2026-05-14 20:01 EST — [NuCana Reports First Quarter 2026 Financial Results and Provides Business Update](https://biopharmsignal.com/news/NCNA/nucana-reports-first-quarter-2026-financial-results-and-provides-business-update) — Source: NuCana plc
- 2026-03-19 20:01 EST — [NuCana Reports Fourth Quarter and Year-End 2025 Financial Results and Provides Business Update](https://biopharmsignal.com/news/NCNA/nucana-reports-fourth-quarter-and-year-end-2025-financial-results-and-provides-business-update) — Source: NuCana plc
- 2026-01-06 13:00 EST — [NuCana Appoints Theresa Bruce as Chief Operating Officer](https://biopharmsignal.com/news/NCNA/nucana-appoints-theresa-bruce-as-chief-operating-officer) — Source: NuCana plc